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Firstly, it should be noted that the sperm, as a living organism and one of the body's fluids carrying DNA, is rich in vitamins, minerals and trace elements. Therefore, any changes in the composition of that fluid may result in changes in the mobility and sperm vitality, hence the fertility of the man.

Researchers point out that sperm counts have been diluted by about one-third over the last decade, but sperm concentration in the sperm fluid also shows an average decrease of 1.9% per year.

Another important factor in the degradation of sperm quality is DNA fragmentation sperm, is a rupture in one or both DNA strands, in sperm chromosomes. It has been found that DNA damages are more common between infertile men and can negatively affect pregnancy, as well as the quality and / or viability of embryos, especially during the early stages of division.

What can you do to treat sperm DNA fragmentation?

Habits or measures that can be adopted by infertile men to reduce the decline in semen segregation and enhance fertility are the following:

• Stop smoking
• Diet rich in antioxidants, because oxidative stress is the main culprit for "breaking" DNA
• Avoiding medications such as cortisone and SSRIs
• Check for any urinary tract infections
• Healthy diet full of colorful fruits and vegetables
• Information from your doctor about vitamins and antioxidants, such as vitamins C and E, coenzyme Q-10 and supplements containing carnitine

Male infertility is a multifactorial disorder. Reducing quantity and changing sperm quality may occur due to interactions between genetic and environmental factors. Contrary to genetic factors, environmental factors can be modified and changed.

Factors affecting the quality and quantity of spermatozoa:

• Lifestyle (eg. smoking)
• Strength \ Age
• Oxidative stress
• Metabolic diseases
• Endocrine gland disorder
• Genetic anomalies
• Anatomical causes
• Toxins
• Environmental factors
• Infections
• Exposure to radioactivity or chemotherapy

It is important to note that diet also plays a large and important role in male fertility. Essentially, proper and balanced nutrition, helps and increases fertility, and if it is incomplete, wrong and inadequate it causes problems in childbearing.

One sachet contains:

• L-carnitine (fumarate): 1725mg
• Acetyl-L-carnitine: 500mg
• Vitamin C: 90mg
• Citric acid: 50mg
• Zinc: 10mg
• Folic acid: 200μg
• Selenium: 50μg
• Vitamin B12: 1,5 μg
• Coenzyme Q10: 20mg

2 sachets per day - one in the morning and one in the evening - for 4-6 months or as long as you are trying to conceive.

Proxeed^® Plus is a lemon-flavoured powder. Mix one sachet with at least 120 ml of orange juice or water and stir.

Proxeed^® Plus should be taken shortly after mixing and not stored to be taken latter.

Since sperm require approximately 74 days to mature and up to 20 additional days to be capable of fertilization, Proxeed^® Plus should be taken for 4-6 months.

The product of rigorous scientific research, evidence and testing, Proxeed^® Plus is recommended by doctors and leading fertility experts around the world to men who want to optimize their sperm health and fertility.

L-carnitine and acetyl L-carnitine are physiological constituents of the seminal plasma and sperm. Acetyl-L-carnitine is the most important carnitine that can be found in the ejaculate. Carnitine plays an important role in fat metabolism, it is important in the transport of fatty acids with a long chain through the mitochondrial membrane into the mitochondrial matrix and to the achievement of energy for cells, in this case of sperm cells.

Fructose is one of the most important components of energy used by sperm ejaculate as an energy source.

Citric acid also plays an important role in ensuring the energy needs of spermatozoa.

Vitamin B12 is important in the process of maturation of the cells and in the synthesis of the DNA, which means that it is essential for the quality of sperm.

Selenium and coenzyme Q10 are powerful antioxidants that stabilize the integrity of the sperm tail, so their deficiency leads to poor sperm motility.

Vitamin C as an antioxidant is present in seminal plasma, and its addition in smokers improves the quality of sperm.

Zinc is important in the production of ejaculate, and together with folic acid improves the functional quality of sperm.

Proxeed^® Plus is a dietary supplement that improves the quality of semen parameters, which are one of the important factors in the process of conception. That quality is composed of mobility, motility, sperm count and sperm morphology.

In 40% of couples that have not achived pregnancy, the main reason is poor quality of semen.

In family planning prenatal and postnatal health is very important. The style and way of life can increase or reduce the possibility of pregnancy. To maximize the chance of pregnancy a healthy life style can help (healthy diet, regular physical activity, absence of smoking and stress).

Proxeed^® Plus is a dietary supplement that can help. The only product which contains L-carnitine and it's active form acetyl L-carnitine in an amount necessary to improve motility and fertility. It affects the maturation and sperm quality, improves and protects energy metabolism, and protects against oxidative stress.

Increases sperm count, improves sperm motility, progressive motility and morphology of spermatozoa

Does not harm and has no contraindications.

Since sperm require approximately 74 days to mature and up to 20 additional days to be capable of fertilisation, Proxeed^® Plus should be taken for 4-6 months.

Ingredients of Proxeed^® Plus have synergistic effect on specific metabolic processes. Proxeed® Plus is suitable for use in techniques of assisted reproduction (IUI, IVF).

Significant studies emphasize the benefit and safety of high-quality ingredients of Proxeed^® Plus which uses Multifunction Ingredient System (MIS multi-system ingredients with more potential of action) to:

• improve and protect the energy metabolism required for sperm
• protect sperm from oxidative stress
• improve sperm maturation and function
• protect sperm cells from apoptosis

Men produce sperm on a continuous basis so it is important for your body to have a constant supply of nutrients and vitamins that are needed for healthy sperm development.

Diet, lack of certain nutrients and lifestyle factors (such as smoking, alcohol and lack of exercise) can all have an impact on sperm quality. Research has shown that specific nutrients, antioxidants, and vitamins can improve sperm quality and health.

On average, sperm require approximately 74 days to mature and up to 20 additional days to become capable of fertilisation. Therefore, lifestyle changes you make today will take 3 or more months to show up in your semen analysis.

Recent studies have shown that sperm counts in men have declined by as much as 30% from 1989 and 2005.

Proxeed^® Plus is a simple, safe and effective way to support male reproductive health.

Tight underwear
The testicles are responsible for producing and storing sperm. Tight underwear can cause a higher scrotal temperature which can reduce sperm quality.

Keep your testicles cool
A man's testicles should be one or two degrees cooler than the rest of his body. Tight underwear, hot showers and hot baths, driving for long distances, and laptops can raise the temperature of the testicles and affect sperm quality.

Alcohol
Cut downDrinking too much alcohol can damage the quality of your sperm. You shouldn’t drink more than three to four units of alcohol a day if you and your partner are trying for a baby.

Caffeinated beverages
There is no consistent evidence that caffeinated beverages can cause fertility problems. But the combination of coffee, drinking and smoking can affect the quality of your sperm.

Smoking- give it up
Smoking is not only bad for your health, it also reduces fertility in both men and women, and can be harmful for the unborn child. Conception – It’s all about timing.

Have sex every day
in the five days leading up to ovulation. The egg survives for less than 24-hours after ovulation, whereas a man’s sperm can live for up to six days in the fallopian tubes. Having regular sex before ovulation means the sperm is ready and waiting.

How should Proxeed® Plus be taken?
Men should take two packets of Proxeed® Plus daily: one (1) packet in the morning and one (1) packet in the evening.Mix the contents of each packet with at least 4 ounces (120 ml) of water or other beverages and consume.

Who should take Proxeed® Plus?
ProXeed® Plus is recommended for all men who:

• want to optimise sperm health and maximise their chances of fathering a child
• are experiencing fertility problems
• are recovering following varicocele repair and vasectomy reversal procedures
• are preparing for assisted reproductive techniques (ART)
• have a poor diet and unhealthy lifestyle: smoke, don’t take regular exercise, feel stressed, drink too much alcohol.. which contributes to poor sperm quality

How long should you take Proxeed® Plus ?
You should take Proxeed® Plus for 4-6 months or for as long as you are trying to conceive. This is because sperm require approximately 74 days to mature and up to 20 additional days to be capable of fertilization . Therefore, initial results may be seen in as few as three (3) months. However, Proxeed® Plus should be taken for at least six (6) months for optimal results. Proxeed® Plus should be taken as long as needed to maintain sperm quality, an essential factor in a couples fertility.

What should I do if I forget to take Proxeed® Plus?
If you forget to take Proxeed® Plus simply resume taking Proxeed® Plus once you realize, then continue to take it on a regular basis. If the interruption is prolonged you will delay experiencing the benefits of Proxeed® plus. Interruptions will have less impact the longer you have been taking Proxeed® Plus.

What role do carnitines play with male fertility?
Carnitines play a key role in sperm energy metabolism. Many clinical studies have shown that carnitines play an important role in sperm function. L-carnitine is a component of both seminal plasma and sperm cells, and plays a role in sperm maturation and potential sperm motility. Acetyl-L-carnitine also serves as a circulating energy source for sperm and provides primary fuel for sperm motility.

Are there any side effects with the use of Proxeed® Plus?
Since the introduction of its parent product, Proxeed®, in late 1998, less than 1% of new patients have reported mild gastrointestinal complaints including upset stomach, heartburn, flatulence (gas), and loose stools. These symptoms can be relieved by: taking 1/2 a packet four times a day; taking Proxeed® Plus mixed in water with meals; and/or avoiding light lemon fruit juices.

Are there any contraindications to taking Proxeed® Plus?
Proxeed® Plus is contraindicated in anyone with known hypersensitivity or allergy to any of the ingredients in Proxeed® plus. It is recommended that you consult with your physician before starting Proxeed® Plus.